The William H. Gass Papers consist largely of his own manuscript material: manuscripts and proof material toward his books, drafts of various stories, essays, and reviews, interviews, and a miscellaneous assortment of notes and other materials. Also present is a substantial amount of professional correspondence, primarily with universities, magazines, and publishers, as well as with his colleagues in academia and in the literary community.

The Jarvis Thurston Papers consist primarily of correspondence relating to Washington University's Department of English and its visiting writers program. The most significant part of the Thurston collection is the correspondence from James T. Farrell to Thurston and Van Duyn. These letters are of a more personal nature and often discuss literary matters such as Van Duyn's work. A small group of manuscripts, notably two drafts of a Thurston short story, "The Cross," is also included.

The Alexander Trocchi Papers include manuscripts of his novels, stories, essays and poems, the extant archives of Merlin, most of his manuscripts and correspondence concerning the Sigma Project, material relating to a large number of projects Trocchi was involved with in the 1960’s, and his journals and notebooks. The Trocchi Papers also house an extensive collection of magazines and ephemera, including material relating to the International Situationist movement.